February 7, 2023

Triptorelin Injection Dosage, Precautions and Side Effects 

Triptorelin is a kind of synthetic hormone that controls multiple body processes. Triptorelin is available in two brands and both treat different conditions.

  1. Trelstar – It is used to treat prostate cancer symptoms in men. Remember, it treats the symptoms only and not cancer.
  2. Triptodur – It is used to treat CPP (Central Precocious Puberty). It is a condition that speeds up puberty in girls and boys (before 8/9 years). 

Triptorelin injections belong to a medication class called GnRH (Gonadotropin-Releasing Hormone). It works by reducing certain body hormone levels. 

What to discuss with the doctor before taking Triptorelin injections?

Before you agree to take Triptorelin, tell your doctor about –

  • Allergies to medications.
  • Any supplements or prescribed medication you are consuming. 
  • Your medical history.
  • About anyone in the family with long-term QT syndrome. It is a condition that increases the chances of developing an irregular heartbeat, which can cause sudden death or fainting. 
  • You are trying to become pregnant or are already pregnant or currently breastfeeding.

You can buy Tritorelin vials from online drug stores with 99% purity. Make sure to get familiar with the proper dosage level to avoid Triptorelin side effects.

The recommended dosage of Triptorelin injections

Triptorelin is available as long-acting (extended-release), so needs to be injected in the thigh or buttock muscle by your healthcare provider. The dosage for Trelstar used to treat prostate cancer is given in one of the following ways –

  • 3.75mg every 4 weeks
  • 11.25mg every 12 weeks
  • 22.5mg every 24 weeks

The dosage and schedule will depend on your symptom severity. The dosage of Triptodur used to treat CPP is 22.5mg every 24 weeks. After the injection is given, patients will experience an increase in hormones within the first couple of weeks. The doctor will monitor the patient to identify if the symptoms worsen or not. 

Some precautions to take

If you are planning to inject the muscle on your own then learn to properly use it. Triptorelin has to be blended with a diluent before using it. Therefore understanding how to mix the liquid and powder properly is needed. Even store the unused vials correctly to avoid any contamination.

Store it away from heat and moisture, but at room temperature. Never freeze! Every bottle is for single use. After using, throw away even if you find medicine left inside. Use a disposable syringe and dispose of them correctly after use. Ensure to keep the vials and their paraphernalia away from pets and children. 

Side effects of Triptorelin injection

Some of the side effects are temporary, but if you experience the following symptoms after the injection call your doctor.

  • Headache
  • Heartburn
  • Sweating or hot flashes
  • Constipation
  • Breast pain
  • Mood swings
  • Depression
  • Cough
  • Pain in the legs or joints
  • Itching or redness or swelling in the injection site
  • Sleep issues

Some serious side effects that need an emergency help from the doctor

  • Hives
  • Itching
  • Rash
  • Hoarseness
  • Difficulty in swallowing or taking a breath
  • Seizures
  • Pain in the back, neck, jaw, and arms
  • Chest pain
  • Swollen face, lips, throat, eyes, and mouth
  • Dizziness
  • Numbness in the extremities
  • Unable to move legs
  • Difficulty in speech
  • Blurred vision
  • Nausea, vomiting, and dry mouth
  • Frequent urination
  • Feeling thirsty
  • Blood in the urine

Children treated with Triptodur for CPP may experience new or deteriorating symptoms of puberty in an initial couple of weeks post-treatment. If girls experience spotting or onset of menstruation in the first couple of months they need to visit their doctor. 

While using Triptorelin follow the doctor’s instructions about food, beverage, or activities limitations. Make sure to call the doctor for guidance if you miss the Triptorelin injection appointment.